Non-Clinical studies

Non-clinical studies are an essential part of the development of novel radiotracers and theranostics.

Increasing regulatory focus on the scientific relevance and translational justification of preclinical data means that careful consideration must be given to study design, model selection, and the overall impact of generated data on the downstream clinical development pathway.

Whether evaluating basic proof-of-principle biodistribution, tissue pharmacology, dosimetry or therapeutic efficacy, CITRAS provides expert support in both the design and critical review of non-clinical programmes.

Designing Preclinical Programmes That Enable Clinical Translation

A scientific poster showing tumor accumulation in mice, changes in tumor volume over time, and survival curves related to a breast cancer model in mice treated with DOTA-hTAB004.

Where required, CITRAS can recommend AAALAC accredited partners and can assist with:

  • Study design

  • Site selection (AAALAC accredited sites only)

  • Reqisite preclinical studies to enable clinical translation

  • Scientific review and support

  • Tech transfer and method development support

  • Trouble shooting and root cause analysis

  • Data interpretation

  • Report review

Four overlapping blue circles with text describing services related to radiochemistry, clinical trial supply, facility design, and regulatory advice.

Our Services

Discuss Your Radiopharmaceutical Programme with Our Senior Team

Independent expertise in radiochemistry, imaging and regulatory strategy - tailored to your development stage.